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EPHA1 (Phospho-Tyr605) rabbit pAb

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis. [provided by RefSeq, Jul 2008],

Product Specifications

Background

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis. [provided by RefSeq, Jul 2008]

Product Name Alternative

Ephrin type-A receptor 1 (hEpha1; EC 2.7.10.1; EPH tyrosine kinase; EPH tyrosine kinase 1; Erythropoietin-producing hepatoma receptor; Tyrosine-protein kinase receptor EPH)

UniProt

P21709

Swiss Prot

P21709

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from human EPHA1 (Phospho-Tyr605)

Target

EPHA1

Clonality

Polyclonal

Source

Rabbit

Applications

IHC; IF; WB

Concentration

1 mg/ml

Dilution

IHC-p 1:50-200, WB 1:500-2000

Buffer

-20°C/1 year

Molecular Weight

108kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

108kD

Fragment

IgG

Subcellular Location

Cell membrane ; Single-pass type I membrane protein .

Other Product Names

Ephrin type-A receptor 1 (hEpha1; EC 2.7.10.1; EPH tyrosine kinase; EPH tyrosine kinase 1; Erythropoietin-producing hepatoma receptor; Tyrosine-protein kinase receptor EPH)

Gene ID (Human)

2041

Available Sizes

Curated Selection

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