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MS-0022

MS-0022 is a Smoothened (SMO) antagonist. MS-0022 can inhibit the Hedgehog (Hh) signaling pathway. MS-0022 can be used in anti-tumor research[1].

Product Specifications

CAS Number

691392-89-9

UNSPSC

12352005

Target

Hedgehog; Smo

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ms-0022.html

Smiles

O=C(NC1=CC=C(C2=CN3C=CC=C(C)C3=N2)C=C1)C4=CC=CC=C4Br

Molecular Formula

C21H16BrN3O

Molecular Weight

406.28

References & Citations

[1]Strand MF, et al. A novel synthetic smoothened antagonist transiently inhibits pancreatic adenocarcinoma xenografts in a mouse model. PLoS One. 2011;6 (6) :e19904.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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