MS-0022
MS-0022 is a Smoothened (SMO) antagonist. MS-0022 can inhibit the Hedgehog (Hh) signaling pathway. MS-0022 can be used in anti-tumor research[1].
Product Specifications
CAS Number
691392-89-9
UNSPSC
12352005
Target
Hedgehog; Smo
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ms-0022.html
Smiles
O=C(NC1=CC=C(C2=CN3C=CC=C(C)C3=N2)C=C1)C4=CC=CC=C4Br
Molecular Formula
C21H16BrN3O
Molecular Weight
406.28
References & Citations
[1]Strand MF, et al. A novel synthetic smoothened antagonist transiently inhibits pancreatic adenocarcinoma xenografts in a mouse model. PLoS One. 2011;6 (6) :e19904.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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