14-Deoxy-11,12-didehydroandrographolide
14-Deoxy-11,12-didehydroandrographolide is an analogue of Andrographolide. 14-Deoxy-11,12-didehydroandrographolide inhibits NF-κB activation.
Product Specifications
CAS Number
[42895-58-9]
Product Name Alternative
14-dehydro Andrographolide; AP10
UNSPSC
12352005
Target
NF-κB
Type
Natural Products
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/14-Deoxy-11,12-didehydroandrographolide.html
Purity
98.63
Solubility
DMF : 100 mg/mL (ultrasonic) |DMSO : 110 mg/mL (ultrasonic)
Smiles
O=C1OCC=C1/C=C/[C@@H]2C(CC[C@]3([H])[C@](C)(CO)[C@H](O)CC[C@@]23C)=C
Molecular Formula
C20H28O4
Molecular Weight
332.43
References & Citations
[1]Guan SP, et al. Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue ofandrographolide, in allergic airway inflammation. J Nat Prod. 2011 Jun 24;74 (6) :1484-90.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
NF-κB
Available Sizes
Curated Selection
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