Galectin-3-IN-5
Product Specifications
UNSPSC Description
Galectin-3-IN-5 (Compound 20) is an orally active inhibitor of galectin-3 (Gal-3), with an IC50 value of 9.2 nM against hGal-3[1].
Target Antigen
Galectin
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/galectin-3-in-5.html
Smiles
CN1N=C(N(C2=C(C(F)(F)F)C=CC(Cl)=C2)C1=S)[C@@H]3O[C@@H]([C@@H]([C@H](N4C=C(C5=C(C(F)=C(C=C5)Br)F)N=N4)[C@H]3O)O)CO
Molecular Weight
697.86
References & Citations
[1]Yoon D S, et al. Atropisomerism Observed in Galactose-Based Monosaccharide Inhibitors of Galectin-3 Comprising 2-Methyl-4-phenyl-2, 4-dihydro-3 H-1, 2, 4-triazole-3-thione[J]. Journal of Medicinal Chemistry, 2024.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162789/Galectin-3-IN-5-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162789/
Clinical Information
No Development Reported
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