BRD4 Inhibitor-31
BRD4 Inhibitor-31 (Example 136) is a BRD4 inhibitor (Kis: 0.234 μM and 0.295 μM for BRD4 BD1 and BRD4 BD2 respectively) . BRD4 Inhibitor-31 can be used for research of inflammatory diseases, cancer, and AIDS[1].
Product Specifications
CAS Number
1446233-35-7
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/brd4-inhibitor-31.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCC(CC1)NC(C2=CC(C3=CN(C)C(C4=C3C=CN4)=O)=C(OC5=CC=C(C=C5F)F)C=C2)=O)OC(C)(C)C
Molecular Formula
C31H32F2N4O5
Molecular Weight
578.61
References & Citations
[1]Bromodomain inhibitors. Patent. WO2013097601
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
BD1; BD2
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