(Phe2, Nle4) -ACTH (1-24) (human, bovine, rat)
(Phe2, Nle4) -ACTH (1-24) (human, bovine, rat) is a fragment of the ACTH hormone. (Phe2, Nle4) -ACTH (1-24) (human, bovine, rat) can be labeled with I125 on Tyr23 to produce a radiolabeled ligand[1].
Product Specifications
CAS Number
97773-00-7
UNSPSC
12352209
Target
Melanocortin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/phe2-nle4-acth-1-24-human-bovine-rat.html
Solubility
10 mM in DMSO
Smiles
OC[C@H](N)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CO)C(N[C@@H](CCCC)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC2=CN=CN2)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(NCC(N[C@@H](CCCCN)C(N4[C@@H](CCC4)C(N[C@@H](C(C)C)C(NCC(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N5[C@@H](CCC5)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](CC6=CC=C(C=C6)O)C(N7[C@@H](CCC7)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC8=CNC9=CC=CC=C89)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C137H212N40O30
Molecular Weight
2899.40
References & Citations
[1]M.R. Hnatowich, et al. ACTH receptors in nervous tissue. High affinity binding–sequestration of [125I][Phe2, Nle4]ACTH 1–24 in homogenates and slices from rat brain. Canadian Journal of Physiology and Pharmacology. 1989, 38-46.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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