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(Phe2, Nle4) -ACTH (1-24) (human, bovine, rat)

(Phe2, Nle4) -ACTH (1-24) (human, bovine, rat) is a fragment of the ACTH hormone. (Phe2, Nle4) -ACTH (1-24) (human, bovine, rat) can be labeled with I125 on Tyr23 to produce a radiolabeled ligand[1].

Product Specifications

CAS Number

97773-00-7

UNSPSC

12352209

Target

Melanocortin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/phe2-nle4-acth-1-24-human-bovine-rat.html

Solubility

10 mM in DMSO

Smiles

OC[C@H](N)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CO)C(N[C@@H](CCCC)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC2=CN=CN2)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(NCC(N[C@@H](CCCCN)C(N4[C@@H](CCC4)C(N[C@@H](C(C)C)C(NCC(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N5[C@@H](CCC5)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](CC6=CC=C(C=C6)O)C(N7[C@@H](CCC7)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC8=CNC9=CC=CC=C89)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C137H212N40O30

Molecular Weight

2899.40

References & Citations

[1]M.R. Hnatowich, et al. ACTH receptors in nervous tissue. High affinity binding–sequestration of [125I][Phe2, Nle4]ACTH 1–24 in homogenates and slices from rat brain. Canadian Journal of Physiology and Pharmacology. 1989, 38-46.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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