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Brevicidine

Brevicidine is a non-ribosomally synthesized antimicrobial peptide with potent antibacterial activity against Gram-negative pathogens. Brevicidine disrupts the morphology of bacteria by binding to polysaccharides (LPS) on bacterial cell membranes to form holes[1].

Product Specifications

CAS Number

[2676889-05-5]

UNSPSC

12352209

Target

Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/brevicidine.html

Smiles

O=C(N[C@@](C(NCC(N[C@H](C(O[C@@H]1C)=O)CO)=O)=O)([H])[C@@H](C)CC)[C@H]1NC([C@@H](NC([C@@H](CCCN)NC(CNC([C@H](CCCN)NC([C@@H](CCCN)NC([C@H](NC([C@H](NC([C@@H](CC(N)=O)NC(CCC(C)CC)=O)=O)CC2=CC=C(C=C2)O)=O)CC3=CNC4=CC=CC=C34)=O)=O)=O)=O)=O)CC5=CNC6=CC=CC=C56)=O

Molecular Formula

C74H106N18O17

Molecular Weight

1519.74

References & Citations

[1]Zhao X, et al. Mimicry of a non-ribosomally produced antimicrobial, brevicidine, by ribosomal synthesis and post-translational modification[J]. Cell Chemical Biology, 2020, 27 (10) : 1262-1271. e4.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P10519/Brevicidine-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P10519/

Scientific Category

Peptides

Clinical Information

No Development Reported

Curated Selection

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