Human Factor Xab without GLA Domain

<strong>Human Factor Xab without GLA Domain</strong>_x000D_ <strong>Catalog number:</strong> B2013277_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 191 IU/mg_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> Human Factor Xab gla domainless_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Winter WE, Flax SD, Harris NS. Coagulation Testing in the Core Laboratory Lab Med. 2017 Nov 8;48(4):295-313._x000D_ 2: Blostein MD, Rigby AC, Jacobs M, Furie B, Furie BC. The Gla domain of human prothrombin has a binding site for factor Va J Biol Chem. 2000 Dec 1;275(48):38120-6._x000D_ 3: Padmanabhan K, Padmanabhan KP, Tulinsky A, Park CH, Bode W, Huber R, Blankenship DT, Cardin AD, Kisiel W. Structure of human des(1-45) factor Xa at 2.2 A resolution J Mol Biol. 1993 Aug 5;232(3):947-66._x000D_ 4: Soeda T, Nogami K, Nishiya K, Takeyama M, Ogiwara K, Sakata Y, Yoshioka A, Shima M. The factor VIIIa C2 domain (residues 2228-2240) interacts with the factor IXa Gla domain in the factor Xase complex J Biol Chem. 2009 Feb 6;284(6):3379-88._x000D_ 5: Sugo T, Nakamikawa C, Tanabe S, Matsuda M. Activation of prothrombin by factor Xa bound to the membrane surface of human umbilical vein endothelial cells: its catalytic efficiency is similar to that of prothrombinase complex on platelets J Biochem. 1995 Feb;117(2):244-50._x000D_ 6: Itoh S, Yokoyama R, Kamoshida G, Fujiwara T, Okada H, Takii T, Tsuji T, Fujii S, Hashizume H, Onozaki K. Staphylococcal superantigen-like protein 10 (SSL10) inhibits blood coagulation by binding to prothrombin and factor Xa via their γ-carboxyglutamic acid (Gla) domain J Biol Chem. 2013 Jul 26;288(30):21569-80._x000D_ 7: Bajaj SP. Region of factor IXa protease domain that interacts with factor VIIIa: analysis of select hemophilia B mutants Thromb Haemost. 1999 Aug;82(2):218-25._x000D_ 8: Wong MY, Gurr JA, Walsh PN. The second epidermal growth factor-like domain of human factor IXa mediates factor IXa binding to platelets and assembly of the factor X activating complex Biochemistry. 1999 Jul 13;38(28):8948-60._x000D_ 9: Joseph JS, Kini RM. Snake venom prothrombin activators homologous to blood coagulation factor Xa Haemostasis. 2001 May-Dec;31(3-6):234-40._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/20156644">10: Lee CJ, Chandrasekaran V, Wu S, Duke RE, Pedersen LG. Recent estimates of the structure of the factor VIIa (FVIIa)/tissue factor (TF) and factor Xa (FXa) ternary complex Thromb Res. 2010 Apr;125 Suppl 1:S7-S10. </a>_x000D_ _x000D_ <strong>Products Related to Human Factor Xab without GLA Domain can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>