A-849529

A-849529 is an acid metabolite of ABT-869 (HY-50751) . ABT-869 is a potent and orally active multi-target inhibitor of VEGFR and PDGFR family[1].

Product Specifications

CAS Number

[819058-88-3]

UNSPSC

12352005

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/a-849529.html

Smiles

O=C(C1=CC=C(C(NC(NC2=CC=C(C3=C4C(N)=NNC4=CC=C3)C=C2)=O)=C1)F)O

Molecular Formula

C21H16FN5O3

Molecular Weight

405.38

References & Citations

[1]Rodila rc, et, al. A high-throughput, fully automated liquid/liquid extraction liquid chromatography/mass spectrometry method for the quantitation of a new investigational drug ABT-869 and its metabolite A-849529 in human plasma samples. Rapid Commun Mass Spectrom. 2006;20 (20) :3067-75.