Benzothiazole-CH2 (NH-CO-CH2Cl) -CONH-CH2-Ph
Benzothiazole-CH2 (NH-CO-CH2Cl) -CONH-CH2-Ph is a ligand for E3 ubiquitin ligase. Benzothiazole-CH2 (NH-CO-CH2Cl) -CONH-CH2-Ph can be connected to the ligand for protein by a linker to form 22-SLF.
Product Specifications
CAS Number
3079209-79-0
UNSPSC
12352005
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/benzothiazole-ch2-nh-co-ch2cl-conh-ch2-ph.html
Smiles
O=C(CCl)NC(C1=NC2=C(S1)C=CC=C2)C(NCC3=CC=CC=C3)=O
Molecular Formula
C18H16ClN3O2S
Molecular Weight
373.86
References & Citations
[1]Ananya A Basu, A CRISPR activation screen identifies FBXO22 supporting targeted protein degradation. bioRxiv[Preprint]. 2023 Sep 16:2023.09.15.557708.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Von Hippel-Lindau (VHL)
Frequently Asked Questions
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