GW409544
Product Specifications
UNSPSC Description
GW409544 is a potent PPARα and PPARγ activator, with EC50 values of 2.3 nM and 0.28 nM for PPARα and PPARγ, respectively. GW409544 can be used for the research of metabolic and cardiovascular diseases[1].
Target Antigen
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/gw409544.html
Smiles
O=C(C1=CC=CC=C1)/C=C(C)\N[C@H](C(O)=O)CC(C=C2)=CC=C2OCCC3=C(C)OC(C4=CC=CC=C4)=N3
Molecular Weight
510.58
References & Citations
[1]Xu HE, et al. Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13919-24.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-121448/GW409544-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-121448/
Clinical Information
Phase 1
CAS Number
258345-41-4
Curated Selection
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