Serpin F1/Pigment epithelium-derived factor/PEDF
Recombinant Mouse Serine Protease Inhibitor-clade F1 is produced by our E.coli expression system and the target gene encoding Asp43-Thr417 is expressed.
Product Specifications
Background
Serpin F1 is secreted Neurotrophic protein and belongs to the serpin family. Serpin F1 Highly expressed in the liver, gastric glandular mucosa and renal tubules. It is also expressed in the brain, heart, lung retina and testes. It induces extensive neuronal differentiation in retinoblastoma cells. It is potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, exhibits no serine protease inhibitory activity.
Synonyms
Pigment epithelium-derived factor; Pedf; Sdf3; Caspin; Serpin F1; Stromal cell-derived factor 3.
Expression System
E. Coli
Endotoxin
Less than 0.1 ng/ µg (1 IEU/ µg) as determined by LAL test.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Form
Liquid
Shipping Conditions
The product is shipped on dry ice/ice packs.
Formulation
Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl, pH7.4.
Species
Mouse
Shipping Temperature
Dry Ice/Ice Packs
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