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Serpin F1/Pigment epithelium-derived factor/PEDF

Recombinant Mouse Serine Protease Inhibitor-clade F1 is produced by our E.coli expression system and the target gene encoding Asp43-Thr417 is expressed.

Product Specifications

Background

Serpin F1 is secreted Neurotrophic protein and belongs to the serpin family. Serpin F1 Highly expressed in the liver, gastric glandular mucosa and renal tubules. It is also expressed in the brain, heart, lung retina and testes. It induces extensive neuronal differentiation in retinoblastoma cells. It is potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, exhibits no serine protease inhibitory activity.

Synonyms

Pigment epithelium-derived factor; Pedf; Sdf3; Caspin; Serpin F1; Stromal cell-derived factor 3.

Expression System

E. Coli

Endotoxin

Less than 0.1 ng/ µg (1 IEU/ µg) as determined by LAL test.

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Form

Liquid

Shipping Conditions

The product is shipped on dry ice/ice packs.

Formulation

Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl, pH7.4.

Species

Mouse

Shipping Temperature

Dry Ice/Ice Packs

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