Ephrin-B2
Recombinant Human Ephrin-B2 is produced by our Mammalian expression system and the target gene encoding Ile28-Ala229 is expressed with a 6His tag at the C-terminus.
Product Specifications
Background
Ephrin-B2 is a type I transmembrane protein and belongs the Ephrin family. It binds to the receptor tyrosine kinases, such as EPHA4, EPHB4 and EPHA3. Ephrin-B2 has been implicated in mediating developmental events, especially in the nervous system, erythropoiesis and tumour metastasis. Ligation of Ephrin-B2 with complementary EphB receptors on adjacent cells results in a combination of forward (EphB receptors) and reverse (Ephrin-B2) signalling, which is central to tissue development and remodelling functions. In addition, Ephrin-B2 may play a role in constraining the orientation of longitudinally projecting axons.
Synonyms
Ephrin-B2; EPH-Related Receptor Tyrosine Kinase Ligand 5; LERK-5; HTK Ligand; HTK-L; EFNB2; EPLG5; HTKL; LERK5
Expression System
Human cells
Endotoxin
Less than 0.1 ng/ µg (1 IEU/ µg) as determined by LAL test.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Form
Lyophilized
Shipping Conditions
The product is shipped at ambient temperature.
Formulation
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Species
Human
Shipping Temperature
Ambient
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