Kallikrein 4/EMSP1/KLK4
Recombinant Human Kallikrein 4 is produced by our Mammalian expression system and the target gene encoding Ser27-Ser254 is expressed with a 6His tag at the C-terminus.
Product Specifications
Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen members of the Kallikrein subfamily located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
Synonyms
Kallikrein-4; Enamel Matrix Serine Proteinase 1; Kallikrein-Like Protein 1; KLK-L1; Prostase; Serine Protease 17; KLK4; EMSP1; PRSS17; PSTS
Expression System
Human cells
Endotoxin
Less than 0.1 ng/ µg (1 IEU/ µg) as determined by LAL test.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Form
Lyophilized
Shipping Conditions
The product is shipped at ambient temperature.
Formulation
Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0.
Species
Human
Shipping Temperature
Ambient
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