H mgB1/H mg-1
Recombinant Human High Mobility Group Protein B1 is produced by our Mammalian expression system and the target gene encoding Gly2-Glu215 is expressed with a 6His tag at the C-terminus.
Product Specifications
Background
High mobility group protein B1 is a member of the H mgB family consisting of three members, H mgB1, H mgB2 and H mgB3.It Contains 2 H mg box DNA-binding domains entitled box A and box B and It is a highly negative-charged C terminus. As a nuclear protein, H mgB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile, it is revealed that H mgB1 can also act as a cytokine extracellularlly and regulates monocyte, T cell, dendritic cell activities in inflammatory responses.
Synonyms
High Mobility Group Protein B1; High Mobility Group Protein 1; H mg-1; H mgB1; H mg1
Expression System
Human cells
Endotoxin
Less than 0.1 ng/ µg (1 IEU/ µg) as determined by LAL test.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Form
Lyophilized
Shipping Conditions
The product is shipped at ambient temperature.
Formulation
Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0.
Species
Human
Shipping Temperature
Ambient
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