Recombinant FAK Protein

<strong>Recombinant FAK Protein</strong>_x000D_ <strong>Catalog number:</strong> B2017492_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> ~145.394 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> PTK2, FADK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Shen J, Cao B, Wang Y, Ma C, Zeng Z, Liu L, Li X, Tao D, Gong J, Xie D. Hippo component YAP promotes focal adhesion and tumour aggressiveness via transcriptionally activating THBS1/FAK signalling in breast cancer J Exp Clin Cancer Res. 2018 Jul 28;37(1):175._x000D_ 2: Lu Q, Wang J, Jiang J, Wang S, Jia Q, Wang Y, Li W, Zhou Q, Lv L, Li Q. rLj-RGD3, a Novel Recombinant Toxin Protein from Lampetra japonica, Protects against Cerebral Reperfusion Injury Following Middle Cerebral Artery Occlusion Involving the Integrin-PI3K/Akt Pathway in Rats PLoS One. 2016 Oct 21;11(10):e0165093._x000D_ 3: Le Y, Zhu BM, Harley B, Park SY, Kobayashi T, Manis JP, Luo HR, Yoshimura A, Hennighausen L, Silberstein LE. SOCS3 protein developmentally regulates the chemokine receptor CXCR4-FAK signaling pathway during B lymphopoiesis Immunity. 2007 Nov;27(5):811-23._x000D_ 4: Song M, Tian F, Xia H, Xie Y. Repulsive guidance molecule a suppresses seizures and mossy fiber sprouting via the FAK‑p120RasGAP‑Ras signaling pathway Mol Med Rep. 2019 Apr;19(4):3255-3262._x000D_ 5: Niu X, Han Q, Li X, Li J, Liu Y, Li Y, Wu Y, Zhang K. EDIL3 influenced the αvβ3-FAK/MEK/ERK axis of endothelial cells in psoriasis J Cell Mol Med. 2022 Oct;26(20):5202-5212._x000D_ 6: Basson MD, Zeng B, Wang S. Akt1 binds focal adhesion kinase via the Akt1 kinase domain independently of the pleckstrin homology domain J Physiol Pharmacol. 2015 Oct;66(5):701-9._x000D_ 7: Peng JM, Chen YH, Hung SW, Chiu CF, Ho MY, Lee YJ, Lai TC, Hsiao M, Liang CM, Liang SM. Recombinant viral protein promotes apoptosis and suppresses invasion of ovarian adenocarcinoma cells by targeting α5β1 integrin to down-regulate Akt and MMP-2 Br J Pharmacol. 2012 Jan;165(2):479-93._x000D_ 8: Bartolomé RA, García-Palmero I, Torres S, López-Lucendo M, Balyasnikova IV, Casal JI. IL13 Receptor α2 Signaling Requires a Scaffold Protein, FAM120A, to Activate the FAK and PI3K Pathways in Colon Cancer Metastasis Cancer Res. 2015 Jun 15;75(12):2434-44._x000D_ 9: Bond M, Sala-Newby GB, Newby AC. Focal adhesion kinase (FAK)-dependent regulation of S-phase kinase-associated protein-2 (Skp-2) stability. A novel mechanism regulating smooth muscle cell proliferation J Biol Chem. 2004 Sep 3;279(36):37304-10._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/12932330">10: Carragher NO, Westhoff MA, Fincham VJ, Schaller MD, Frame MC. A novel role for FAK as a protease-targeting adaptor protein: regulation by p42 ERK and Src Curr Biol. 2003 Aug 19;13(16):1442-50. </a>_x000D_ _x000D_ <strong>Products Related to Recombinant FAK Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>