Ficellomycin
Product Specifications
UNSPSC Description
Ficellomycin is a nitrogen-containing bicyclic antibiotic with strong activity against Gram-positive bacteria, including multidrug-resistant strains of Staphylococcus aureus. Ficellomycin works by inducing the formation of defective 34S DNA fragments, which interfere with the semi-conservative DNA replication process. These fragments lack the ability to integrate into larger DNA segments and eventually form a complete bacterial chromosome. Ficellomycin can be used in research for various bacterial diseases[1].
Target Antigen
Antibiotic; Bacterial; DNA/RNA Synthesis
Type
Natural Products
Related Pathways
Anti-infection;Cell Cycle/DNA Damage
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ficellomycin.html
Smiles
[H][C@]1(C[C@@H]([C@@H]2CN21)NC(N)=N)C(C(O)=O)NC([C@H](C(C)C)N)=O
Molecular Weight
312.37
References & Citations
[1]He X, et al. Ficellomycin: an aziridine alkaloid antibiotic with potential therapeutic capacity. Appl Microbiol Biotechnol. 2018 May;102(10):4345-4354.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-121348/Ficellomycin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-121348/
Clinical Information
No Development Reported
CAS Number
59458-27-4
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