IKBKG antibody

This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

NF-kappa-B essential modulator (NEMO) |FIP-3|IkB kinase-associated protein 1 (IKKAP1) |Inhibitor of nuclear factor kappa-B kinase subunit gamma (I-kappa-B kinase subunit gamma, IKK-gamma, IKKG, IkB kinase subunit gamma) |NF-kappa-B essential modifier|IKBKG|FIP3|NEMO