IKBKG antibody
Product Specifications
Background
This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.
Synonyms
NF-kappa-B essential modulator (NEMO) |FIP-3|IkB kinase-associated protein 1 (IKKAP1) |Inhibitor of nuclear factor kappa-B kinase subunit gamma (I-kappa-B kinase subunit gamma, IKK-gamma, IKKG, IkB kinase subunit gamma) |NF-kappa-B essential modifier|IKBKG|FIP3|NEMO
Gene ID
8517
UniProt
Q9Y6K9
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
Target
IKBKG
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Immunology, Cardiovascular, Metabolism, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
40-55 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
183-339aa
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