INPPL1 antibody
Product Specifications
Background
The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.
Synonyms
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2|Inositol polyphosphate phosphatase-like protein 1 (INPPL-1) |Protein 51C|SH2 domain-containing inositol 5'-phosphatase 2 (SH2 domain-containing inositol phosphatase 2, SHIP-2) |INPPL1|SHIP2
Gene ID
3636
UniProt
O15357
Host
Rabbit
Reactivity
Human, rat
Immunogen
INPPL1
Target
INPPL1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
138 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
1106-1258aa
Curated Selection
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MBS6327883-02 5x 0.1 mL
OPTN, ID (OPTN, FIP2, GLC1E, HIP7, HYPL, NRP, Optineurin, E3-14.7K-interacting protein, FIP-2, Huntingtin yeast partner L, Huntingtin-interacting protein 7, Huntingtin-interacting protein L, NEMO-related protein, Optic neuropathy-inducing protein, Transcr
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