BAD antibody
Product Specifications
Background
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Synonyms
Bcl2-associated agonist of cell death (BAD)|Bcl-2-binding component 6|Bcl-2-like protein 8 (Bcl2-L-8)|Bcl-xL/Bcl-2-associated death promoter|Bcl2 antagonist of cell death|BAD|BBC6|BCL2L8
Gene ID
572
UniProt
Q92934
Host
Rabbit
Reactivity
Human
Immunogen
BCL2-associated agonist of cell death
Target
BAD
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Neuroscience, Cardiovascular
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
18-25 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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