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IRAK3 antibody

Product Specifications

Background

This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.

Synonyms

Interleukin-1 receptor-associated kinase 3 (IRAK-3) |IL-1 receptor-associated kinase M (IRAK-M) |Inactive IL-1 receptor-associated kinase 3|IRAK3

Gene ID

11213

UniProt

Q9Y616

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

IRAK3

Target

IRAK3

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Purification

Immunogen affinity purified

Dilution

WB: 1:500 - 1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

68 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB

Immunogen Sequence

Peptide

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