IRAK3 antibody
Product Specifications
Background
This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.
Synonyms
Interleukin-1 receptor-associated kinase 3 (IRAK-3) |IL-1 receptor-associated kinase M (IRAK-M) |Inactive IL-1 receptor-associated kinase 3|IRAK3
Gene ID
11213
UniProt
Q9Y616
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
IRAK3
Target
IRAK3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
68 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
Immunogen Sequence
Peptide
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