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GSDMB antibody

Product Specifications

Background

The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores (PubMed:27281216) . The physiological relevance of this observation is unknown (Probable) .

Synonyms

Gasdermin-B|Gasdermin-like protein|Gasdermin-B, N-terminal (GSDMB-NT, p30) |Gasdermin-B, C-terminal (GSDMB-CT, p16) |GSDMB|GSDML

Gene ID

55876

UniProt

Q8TAX9

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Gasdermin B

Target

GSDMB

Clonality

Polyclonal

Isotype

IgG

Applications

WB

Field of Research

Cell Division and Proliferation

Purification

Immunogen affinity purified

Dilution

WB: 1:200-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

47 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

WB

Immunogen Sequence

1-275aa

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