EGFR antibody
Product Specifications
Background
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Synonyms
Epidermal growth factor receptor|Proto-oncogene c-ErbB-1|Receptor tyrosine-protein kinase erbB-1|EGFR|ERBB|ERBB1|HER1
Gene ID
1956
UniProt
P00533
Host
Mouse
Reactivity
Human
Immunogen
Epidermal growth factor receptor
Target
EGFR
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction, Immunology, Cancer
Purification
Protein A+G purified
Dilution
WB: 1:2000 - 1:10000; IHC: 1:100 - 1:1000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
140-160 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
2C9
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
291-534aa
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