FCGR3A antibody
Product Specifications
Background
CD16 is a 50-70-kDa low affinity Fc receptor found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. CD16 mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. CD16 has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), encoded by two nearly identical genes, FCGR3A and the FCGR3B.
Synonyms
Low affinity immunoglobulin gamma Fc region receptor III-A (IgG Fc receptor III-A) |CD16-II|CD16a antigen|Fc-gamma RIII-alpha (Fc-gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcgammaRIIIA) |FcR-10|IgG Fc receptor III-2|FCGR3A|CD16A|FCG3|FCGR3|IGFR3
Gene ID
2214
UniProt
P08637
Host
Rabbit
Reactivity
Human
Immunogen
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
Target
FCGR3A
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction, Cardiovascular, Immunology, Cancer, Stem Cells
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IHC: 1:50-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
55 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
17-208
Curated Selection
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