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PLCB1 antibody

Product Specifications

Background

The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1|PLC-154|Phosphoinositide phospholipase C-beta-1|Phospholipase C-I (PLC-I) |Phospholipase C-beta-1 (PLC-beta-1) |PLCB1|KIAA0581

Gene ID

23236

UniProt

Q9NQ66

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Phospholipase C, beta 1

Target

PLCB1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Signal Transduction

Purification

Immunogen affinity purified

Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

139 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

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