PLCB1 antibody
Product Specifications
Background
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1|PLC-154|Phosphoinositide phospholipase C-beta-1|Phospholipase C-I (PLC-I) |Phospholipase C-beta-1 (PLC-beta-1) |PLCB1|KIAA0581
Gene ID
23236
UniProt
Q9NQ66
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Phospholipase C, beta 1
Target
PLCB1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
139 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
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