PTCH1 antibody
Product Specifications
Background
Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH) . Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.
Synonyms
Protein patched homolog 1 (PTC, PTC1) |PTCH1|PTCH
Gene ID
5727
UniProt
Q13635
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Patched homolog 1
Target
PTCH1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC
Field of Research
Neuroscience, Cell Division and Proliferation
Purification
Immunogen affinity purified
Dilution
IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
161 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
135268-APC 100 µL
VPREB3 (Pre-B Lymphocyte Protein 3, Protein VPreB3, N27C7-2, UNQ355/PRO619, 8HS20) (APC)
Ask
View Details