CX3CR1 antibody
Product Specifications
Background
Receptor for the CX3C chemokine fractalkine (CX3CL1) ; binds to CX3CL1 and mediates both its adhesive and migratory functions (PubMed:9390561, PubMed:23125415) . Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro) (PubMed:9726990) . Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1 (PubMed:14607932) .
Synonyms
CX3C chemokine receptor 1 (C-X3-C CKR-1, CX3CR1) |Beta chemokine receptor-like 1 (CMK-BRL-1, CMK-BRL1) |Fractalkine receptor|G-protein coupled receptor 13|V28|CX3CR1|CMKBRL1|GPR13
Gene ID
1524
UniProt
P49238
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Chemokine (C-X3-C motif) receptor 1
Target
CX3CR1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Neuroscience, Stem Cells, Immunology, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
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