Phospho-MTOR (S2448) antibody
Product Specifications
Background
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.
Synonyms
Serine/threonine-protein kinase mTOR|FK506-binding protein 12-rapamycin complex-associated protein 1|FKBP12-rapamycin complex-associated protein|Mammalian target of rapamycin (mTOR) |Mechanistic target of rapamycin|Rapamycin and FKBP12 target 1|Rapamycin target protein 1|MTOR|FRAP|FRAP1|FRAP2|RAFT1|RAPT1
Gene ID
2475
UniProt
P42345
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Phospho-MTOR-S2448
Target
Phospho-MTOR (S2448)
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
289 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
Immunogen Sequence
A synthetic phosphorylated peptide around S2448 of human mTOR
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