PTGS2 antibody
Product Specifications
Background
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.
Synonyms
Prostaglandin G/H synthase 2|Cyclooxygenase-2 (COX-2) |PHS II|Prostaglandin H2 synthase 2 (PGH synthase 2, PGHS-2) |Prostaglandin-endoperoxide synthase 2|PTGS2|COX2
Gene ID
5743
UniProt
P35354
Host
Mouse
Reactivity
Human, Mouse
Immunogen
Prostaglandin-endoperoxide synthase 2
Target
PTGS2
Clonality
Monoclonal
Isotype
IgG2a
Applications
ELISA, WB, IHC
Field of Research
Cancer, Cardiovascular, Metabolism
Purification
Protein A+G purified
Dilution
WB: 1:500-1:2000; IHC: 1:100-1:400
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
68 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
4H7
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
18-350aa
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