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TH antibody

Product Specifications

Background

The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Synonyms

Tyrosine 3-monooxygenase|Tyrosine 3-hydroxylase (TH)|TH|TYH

Gene ID

7054

UniProt

P07101

Host

Mouse

Reactivity

Human, Mouse, Rat

Immunogen

tyrosine hydroxylase

Target

TH

Clonality

Monoclonal

Isotype

IgG1

Clone

1A9

Applications

ELISA, WB, IHC, IF

Field of Research

Neuroscience, Signal Transduction, Metabolism

Purification

protein A+G purified

Dilution

WB: 1:500 - 1:5000; IHC: 1:100 - 1:500; IF: 1:100 - 1:500

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

60 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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