IL4 antibody
Product Specifications
Background
The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Synonyms
Interleukin-4 (IL-4) |B-cell stimulatory factor 1 (BSF-1) |Binetrakin|Lymphocyte stimulatory factor 1|Pitrakinra|IL4
Gene ID
3565
UniProt
P05112
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Interleukin 4
Target
IL4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Immunology, Cardiovascular, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:1000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
Refer to figures
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
Frequently Asked Questions
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