S100A8 antibody
Product Specifications
Background
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms
Protein S100-A8|Calgranulin-A|Calprotectin L1L subunit|Cystic fibrosis antigen (CFAG) |Leukocyte L1 complex light chain|Migration inhibitory factor-related protein 8 (MRP-8, p8) |S100 calcium-binding protein A8|Urinary stone protein band A|S100A8|CAGA|CFAG|MRP8
Gene ID
6279
UniProt
P05109
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
S100 calcium binding protein A8
Target
S100A8
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Immunology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
11 kDa, 25 kDa, 40 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
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