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HTT antibody

Product Specifications

Background

HTT (huntingtin), also named as HD and IT15, belongs to the huntingtin family. HTT may play a role in microtubule-mediated transport or vesicle function. Defects in HTT are the cause of Huntington disease (HD) which is an autosomal dominant neurodegenerative disorder characterized by involuntary movements (chorea), general motor impairment, psychiatric disorders and dementia.

Synonyms

Huntingtin|Huntington disease protein (HD protein) |Huntingtin, myristoylated N-terminal fragment|HTT|HD|IT15

Gene ID

3064

UniProt

P42858

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Huntingtin

Target

HTT

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IF

Field of Research

Neuroscience

Purification

Immunogen affinity purified

Dilution

WB: 1:500 - 1:2000; IHC: 1:50-1:500; IF: 1:50-1:500

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

348 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IF

Immunogen Sequence

2845-3000aa

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