DVL1 antibody
Product Specifications
Background
DVL1 is one of three DVL homologous proteins (DVL1–3) widely expressed in embryonic development and in the adult central nervous system. Dishevelled proteins are a necessary component of the Wnt and planar cell polarity developmental signaling pathways. Overexpression of DVL1 has been linked to prostate and breast cancers through the Wnt signaling pathway.
Synonyms
Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) |DSH homolog 1|DVL1
Gene ID
1855
UniProt
O14640
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Dishevelled, dsh homolog 1
Target
DVL1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Neuroscience, Signal Transduction, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
70 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
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