HSPA8 antibody
Product Specifications
Background
HSPA8 (also known as HSC70) is a member of the HSPA (HSP70) family of heat-shock proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. HSPA8 is a constitutively expressed cytosol/nuclear protein able to translocate between cytoplasm and nucleus. Recently it has been reported that HSPA8 can interact with α-synuclein, the critical pathological protein of Parkinson’s disease, indicating its implication in neurodegenerative disease. (21832061)
Synonyms
Heat shock cognate 71 kDa protein|Heat shock 70 kDa protein 8|Lipopolysaccharide-associated protein 1 (LAP-1, LPS-associated protein 1) |HSPA8|HSC70|HSP73|HSPA10
Gene ID
3312
UniProt
P11142
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
Hsc70
Target
HSPA8
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, WB, IHC
Field of Research
Neuroscience, Cardiovascular, Metabolism
Purification
Protein A+G purification
Dilution
WB: 1:3000-1:20000; IHC: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
70 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
4E11
Tested Applications
ELISA, WB, IHC
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