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HSPA8 antibody

Product Specifications

Background

HSPA8 (also known as HSC70) is a member of the HSPA (HSP70) family of heat-shock proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. HSPA8 is a constitutively expressed cytosol/nuclear protein able to translocate between cytoplasm and nucleus. Recently it has been reported that HSPA8 can interact with α-synuclein, the critical pathological protein of Parkinson’s disease, indicating its implication in neurodegenerative disease. (21832061)

Synonyms

Heat shock cognate 71 kDa protein|Heat shock 70 kDa protein 8|Lipopolysaccharide-associated protein 1 (LAP-1, LPS-associated protein 1) |HSPA8|HSC70|HSP73|HSPA10

Gene ID

3312

UniProt

P11142

Host

Mouse

Reactivity

Human, Mouse, Rat

Immunogen

Hsc70

Target

HSPA8

Clonality

Monoclonal

Isotype

IgG1

Applications

ELISA, WB, IHC

Field of Research

Neuroscience, Cardiovascular, Metabolism

Purification

Protein A+G purification

Dilution

WB: 1:3000-1:20000; IHC: 1:50-1:500

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

70 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Clone ID

4E11

Tested Applications

ELISA, WB, IHC

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