CASP2 antibody
Product Specifications
Background
CASP2 (Caspase-2) is also named as ICH1, NEDD2 and belongs to the peptidase C14A family.It is involved in the activation cascade of caspases responsible for apoptosis execution and might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.It has 2 isoforms produced by alternative splicing and can exists almost as a dimer in solution (PMID:15865942) .This antibody can recognize the 32 kDa pro-caspase 2 as well as 18 kDa cleaved-caspase 2.
Synonyms
Caspase-2 (CASP-2) |Neural precursor cell expressed developmentally down-regulated protein 2 (NEDD-2) |Protease ICH-1|Caspase-2 subunit p18|Caspase-2 subunit p13|Caspase-2 subunit p12|CASP2|ICH1|NEDD2
Gene ID
835
UniProt
P42575
Host
Mouse
Reactivity
Human
Immunogen
Caspase 2
Target
CASP2
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, WB
Field of Research
Neuroscience, Immunology, Signal Transduction
Purification
Protein A+G purification
Dilution
WB: 1:1000-1:6000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
18, 32, 50 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
2B10
Tested Applications
ELISA, WB
Frequently Asked Questions
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