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YAP1 antibody

Product Specifications

Background

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms

Transcriptional coactivator YAP1 (Yes-associated protein 1) |Protein yorkie homolog|Yes-associated protein YAP65 homolog|YAP1|YAP65

Gene ID

10413

UniProt

P46937

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Yes-associated protein 1, 65kDa

Target

YAP1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IF

Field of Research

Stem Cells, Signal Transduction, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:10 - 1:100

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

72 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IF

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