CD206 antibody
Product Specifications
Background
CD206, also named as MMR, CLEC13D and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. This antibody recognizes the intracellular carboxy-terminal part of CD206 and MRC1L1.
Synonyms
Macrophage mannose receptor 1 (MMR) |C-type lectin domain family 13 member D|C-type lectin domain family 13 member D-like|Human mannose receptor (hMR) |Macrophage mannose receptor 1-like protein 1|MRC1|CLEC13D|CLEC13DL|MRC1L1
Gene ID
4360
UniProt
P22897
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
CD206
Target
CD206
Clonality
Monoclonal
Isotype
IgG2a
Applications
ELISA, IP, WB
Field of Research
Immunology
Purification
Protein A+G purification
Dilution
WB: 1:1000-1:4000; IP: 1:200-1:1000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
170 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
5E3
Tested Applications
ELISA, IP, WB
Immunogen Sequence
Peptide, intracellular domain
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