Phospho-CD3 ζ (Tyr142) antibody
Product Specifications
Background
Defects in CD3D are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (T (-) /B (+) /NK (+) SCID) . A form of severe combined immunodeficiency (SCID), a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent
Synonyms
T-cell surface glycoprotein CD3 zeta chain|T-cell receptor T3 zeta chain|CD247|CD3Z|T3Z|TCRZ
UniProt
P20963
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A synthesized peptide derived from human CD3 ζ (Phospho-Tyr142)
Target
Phospho-CD3 ζ (Tyr142)
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Field of Research
Signal Transduction, Metabolism, Cardiovascular, Immunology, Cancer, Neuroscience, Stem Cells
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
17 kDa, 21 kDa, 36 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
WB
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