CD163 antibody
Product Specifications
Background
CD163 is a transmembrane protein which belongs to the scavenger receptor cysteine-rich(SRCR) superfamily. This protein is a scavenger receptor for the hemoglobin-haptoglobin complex and is a marker for monocytes and macrophages. Soluble CD163(sCD163), as a result of ectodomain shedding during inflammatory activation of macrophages, circulates in blood and has been suggested as a plasma/serum marker for macrophage activity.
Synonyms
Scavenger receptor cysteine-rich type 1 protein M130|Hemoglobin scavenger receptor|Soluble CD163 (sCD163)|CD163|M130
UniProt
Q86VB7
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
CD163
Target
CD163
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, FC
Field of Research
Signal Transduction, Metabolism, Cardiovascular, Immunology, Neuroscience, Stem Cells
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000; IHC: 1:300-1:1000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
140 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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