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SCNN1B antibody

Product Specifications

Background

SCNN1B, also named as SCNEB, ENaCB, Beta-NaCH and Beta-ENaC, belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family and SCNN1B subfamily. Sodium permeable non-voltage-sensitive ion channel is inhibited by the diuretic amiloride. SCNN1B mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. It controls the reabsorption of sodium in kidney, colon, lung and sweat glands. SCNN1B plays a role in taste perception.

Synonyms

Amiloride-sensitive sodium channel subunit beta|Beta-NaCH|Epithelial Na (+) channel subunit beta (Beta-ENaC, ENaCB) |Nonvoltage-gated sodium channel 1 subunit beta|SCNEB|SCNN1B

Gene ID

6338

UniProt

P51168

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Sodium channel, nonvoltage-gated 1, beta

Target

SCNN1B

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Neuroscience

Purification

Immunogen affinity purified

Dilution

WB: 1:200-1:2000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

78 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

Immunogen Sequence

68-401aa

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