ZKSCAN3 antibody
Product Specifications
Background
Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas.
Synonyms
Zinc finger protein with KRAB and SCAN domains 3|Zinc finger and SCAN domain-containing protein 13|Zinc finger protein 306|Zinc finger protein 309|Zinc finger protein 47 homolog (Zf47, Zfp-47) |ZKSCAN3|ZFP47|ZNF306|ZNF309|ZSCAN13
Gene ID
80317
UniProt
Q9BRR0
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Zinc finger with KRAB and SCAN domains 3
Target
ZKSCAN3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:5000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
62 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
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