DAPK3 antibody
Product Specifications
Background
ZIP kinase, also named as ZIPK and Dlk, belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and DAP kinase subfamily. ZIP kinase is a Serine/threonine kinase which acts as a positive regulator of apoptosis. ZIP kinasephosphorylates histone H3 on 'Thr-11' at centromeres during mitosis. ZIP kinase regulates myosin light chain phosphatase through phosphorylation of MYPT1 thereby regulating the assembly of the actin cytoskeleton, cell migration, invasiveness of tumor cells, smooth muscle contraction and neurite outgrowth. It catalyze the reaction: ATP + a protein = ADP + a phosphoprotein.
Synonyms
Death-associated protein kinase 3 (DAP kinase 3)|DAP-like kinase (Dlk)|MYPT1 kinase|Zipper-interacting protein kinase (ZIP-kinase)|DAPK3|ZIPK
UniProt
O43293
Host
Rabbit
Reactivity
Human
Immunogen
death-associated protein kinase 3
Target
DAPK3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:1000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
53 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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