ZC3H12D antibody
Product Specifications
Background
May regulate cell growth likely by suppressing RB1 phosphorylation (PubMed:19531561) . May function as RNase and regulate the levels of target RNA species (Potential) . In association with ZC3H12A enhances the degradation of interleukin IL-6 mRNA level in activated macrophages (PubMed:26134560) . Serve as a tumor suppressor in certain leukemia cells (PubMed:17210687) . Overexpression inhibits the G1 to S phase progression through suppression of RB1 phosphorylation (PubMed:19531561) .
Synonyms
Probable ribonuclease ZC3H12D|MCP-induced protein 4|Transformed follicular lymphoma|Zinc finger CCCH domain-containing protein 12D|p34|ZC3H12D|C6orf95|MCPIP4|TFL
Gene ID
340152
UniProt
A2A288
Host
Rabbit
Reactivity
Human
Immunogen
Zinc finger CCCH-type containing 12D
Target
ZC3H12D
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IHC: 1:20-1:200; IP: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
58 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB
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